BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer
第1/2相
早期終了
NCT03695250
| 対象疾患 | Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8 |
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| 相 | 第1/2相 |
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| スポンサー | Edward Kim |
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| ステータス | 早期終了 |
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| 参加者数 | 8 名 |
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| 介入(薬剤) | IDO1 Inhibitor BMS-986205, Nivolumab |
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| 開始日 | 2018年10月16日 |
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| 完了日 | 2020年11月24日 |
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| 結果公開日 | 2023年8月22日 |
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概要
This phase I/II trial studies the side effects and best dose of IDO1 inhibitor BMS-986205 (BMS-986205) when given together with nivolumab and how well it works as first or second line therapy in treating patients with liver cancer. BMS-986205 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving BMS-986205 and nivolumab may work better in treating patients with liver cancer.
Adverse Events (AE)
Up to 2 years. · participants
| Treatment (BMS-986205 and Nivolumab) | 2 participants |
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| Treatment (BMS-986205 and Nivolumab) | 1 participants |
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| Treatment (BMS-986205 and Nivolumab) | 1 participants |
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| Treatment (BMS-986205 and Nivolumab) | 1 participants |
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| Treatment (BMS-986205 and Nivolumab) | 1 participants |
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| Treatment (BMS-986205 and Nivolumab) | 1 participants |
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Objective Response Rate (ORR)
Up to approximately 2 years, 1 month. · percentage of participans
| Treatment (BMS-986205 and Nivolumab) | 12.5 percentage of participans |
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BENITIONS で見る
ClinicalTrials.gov の原文を見る
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このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。