BENITIONSClinical Trial Intelligence

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

1/2期 提前终止 NCT03695250

适应症Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8
分期1/2期
申办方Edward Kim
状态提前终止
受试者人数8 人
干预(药物)IDO1 Inhibitor BMS-986205, Nivolumab
开始日期2018年10月16日
完成日期2020年11月24日
结果公布日2023年8月22日

摘要

This phase I/II trial studies the side effects and best dose of IDO1 inhibitor BMS-986205 (BMS-986205) when given together with nivolumab and how well it works as first or second line therapy in treating patients with liver cancer. BMS-986205 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving BMS-986205 and nivolumab may work better in treating patients with liver cancer.

Adverse Events (AE)

Up to 2 years. · participants

Treatment (BMS-986205 and Nivolumab)2 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants

Objective Response Rate (ORR)

Up to approximately 2 years, 1 month. · percentage of participans

Treatment (BMS-986205 and Nivolumab)12.5 percentage of participans

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。