BENITIONSClinical Trial Intelligence

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

1/2상 조기 종료 NCT03695250

대상 질환Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8
임상 단계1/2상
스폰서Edward Kim
상태조기 종료
참여자 수8 명
중재(약물)IDO1 Inhibitor BMS-986205, Nivolumab
시작일2018년 10월 16일
완료일2020년 11월 24일
결과 공개일2023년 8월 22일

요약

This phase I/II trial studies the side effects and best dose of IDO1 inhibitor BMS-986205 (BMS-986205) when given together with nivolumab and how well it works as first or second line therapy in treating patients with liver cancer. BMS-986205 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving BMS-986205 and nivolumab may work better in treating patients with liver cancer.

Adverse Events (AE)

Up to 2 years. · participants

Treatment (BMS-986205 and Nivolumab)2 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants
Treatment (BMS-986205 and Nivolumab)1 participants

Objective Response Rate (ORR)

Up to approximately 2 years, 1 month. · percentage of participans

Treatment (BMS-986205 and Nivolumab)12.5 percentage of participans

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