BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Фаза 1/2 Прекращено NCT03695250

Кратко

This phase I/II trial studies the side effects and best dose of IDO1 inhibitor BMS-986205 (BMS-986205) when given together with nivolumab and how well it works as first or second line therapy in treating patients with liver cancer. BMS-986205 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving BMS-986205 and nivolumab may work better in treating patients with liver cancer.

Adverse Events (AE)

Up to 2 years. · participants

Objective Response Rate (ORR)

Up to approximately 2 years, 1 month. · percentage of participans

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• Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hep — AstraZeneca
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• Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis — National Cancer Institute (NCI)

Все исследования