BENITIONSClinical Trial Intelligence

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

第2相 実施中(募集終了) NCT04175912

対象疾患Metastatic Cholangiocarcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage III Intrahepatic Cholangiocarcinoma AJCC v8
第2相
スポンサーNational Cancer Institute (NCI)
ステータス実施中(募集終了)
参加者数40 名
介入(薬剤)Carboplatin, Paclitaxel, Pevonedistat
開始日2020年3月16日
完了日2023年11月27日
結果公開日2025年1月7日

概要

This phase II trial studies how well pevonedistat alone or in combination with chemotherapy (paclitaxel and carboplatin) works in treating patients with bile duct cancer of the liver. Pevonedistat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This study may help the study doctors find out how well pevonedistat shrinks bile duct cancer of the liver when given alone and when in combination with paclitaxel and carboplatin.

Objective Response

Every 3 months for the first year and every 6 months for years 2-3 · Participants

Arm A (Pevonedistat)0 Participants
Arm B (Pevonedistat, Paclitaxel, Carboplatin)0 Participants
Arm A (Pevonedistat)17 Participants
Arm B (Pevonedistat, Paclitaxel, Carboplatin)17 Participants

BENITIONS で見る ClinicalTrials.gov の原文を見る

同じ疾患の他の治験

すべての治験

このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。