BENITIONSClinical Trial Intelligence

GI Permeability Change in Response to Aquamin®

2期 已完成 NCT04855799

适应症Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea
分期2期
申办方James Varani
状态已完成
受试者人数35 人
干预(药物)Aquamin
开始日期2021年11月2日
完成日期2024年3月11日
结果公布日2026年6月8日

摘要

This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.

Change in the Lactulose:Mannitol Ratio in Urine by Comparing Values at 90-days (Post-intervention) to Baseline (Pre-intervention) Levels.

Baseline (pre-intervention), 90 days (post-intervention)

Mannitol Levels in Urine Samples

90 days · mgs

Aquamin® - Healthy Subjects68.54 ± 85.03 mgs
Aquamin® - Subjects With Ulcerative Colitis110.35 ± 92.70 mgs
Aquamin® - Healthy Subjects106.95 ± 86.68 mgs
Aquamin® - Subjects With Ulcerative Colitis51.60 ± 23.30 mgs
Aquamin® - Healthy Subjects829.14 ± 497.29 mgs
Aquamin® - Subjects With Ulcerative Colitis1277.08 ± 503.40 mgs
p-value0.322

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。