GI Permeability Change in Response to Aquamin®
2期
已完成
NCT04855799
| 适应症 | Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea |
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| 分期 | 2期 |
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| 申办方 | James Varani |
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| 状态 | 已完成 |
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| 受试者人数 | 35 人 |
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| 干预(药物) | Aquamin |
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| 开始日期 | 2021年11月2日 |
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| 完成日期 | 2024年3月11日 |
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| 结果公布日 | 2026年6月8日 |
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摘要
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.
Change in the Lactulose:Mannitol Ratio in Urine by Comparing Values at 90-days (Post-intervention) to Baseline (Pre-intervention) Levels.
Baseline (pre-intervention), 90 days (post-intervention)
Mannitol Levels in Urine Samples
90 days · mgs
| Aquamin® - Healthy Subjects | 68.54 ± 85.03 mgs |
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| Aquamin® - Subjects With Ulcerative Colitis | 110.35 ± 92.70 mgs |
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| Aquamin® - Healthy Subjects | 106.95 ± 86.68 mgs |
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| Aquamin® - Subjects With Ulcerative Colitis | 51.60 ± 23.30 mgs |
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| Aquamin® - Healthy Subjects | 829.14 ± 497.29 mgs |
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| Aquamin® - Subjects With Ulcerative Colitis | 1277.08 ± 503.40 mgs |
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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。