GI Permeability Change in Response to Aquamin®
Фаза 2
Завершено
NCT04855799
| Заболевание | Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea |
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| Фаза | Фаза 2 |
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| Спонсор | James Varani |
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| Статус | Завершено |
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| Участники | 35 участн. |
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| Вмешательство | Aquamin |
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| Дата начала | 2.11.2021 |
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| Дата завершения | 11.03.2024 |
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| Публикация результатов | 8.06.2026 |
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Кратко
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.
Change in the Lactulose:Mannitol Ratio in Urine by Comparing Values at 90-days (Post-intervention) to Baseline (Pre-intervention) Levels.
Baseline (pre-intervention), 90 days (post-intervention)
Mannitol Levels in Urine Samples
90 days · mgs
| Aquamin® - Healthy Subjects | 68.54 ± 85.03 mgs |
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| Aquamin® - Subjects With Ulcerative Colitis | 110.35 ± 92.70 mgs |
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| Aquamin® - Healthy Subjects | 106.95 ± 86.68 mgs |
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| Aquamin® - Subjects With Ulcerative Colitis | 51.60 ± 23.30 mgs |
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| Aquamin® - Healthy Subjects | 829.14 ± 497.29 mgs |
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| Aquamin® - Subjects With Ulcerative Colitis | 1277.08 ± 503.40 mgs |
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