BENITIONSClinical Trial Intelligence

GI Permeability Change in Response to Aquamin®

Фаза 2 Завершено NCT04855799

ЗаболеваниеUlcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea
ФазаФаза 2
СпонсорJames Varani
СтатусЗавершено
Участники35 участн.
ВмешательствоAquamin
Дата начала2.11.2021
Дата завершения11.03.2024
Публикация результатов8.06.2026

Кратко

This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.

Change in the Lactulose:Mannitol Ratio in Urine by Comparing Values at 90-days (Post-intervention) to Baseline (Pre-intervention) Levels.

Baseline (pre-intervention), 90 days (post-intervention)

Mannitol Levels in Urine Samples

90 days · mgs

Aquamin® - Healthy Subjects68.54 ± 85.03 mgs
Aquamin® - Subjects With Ulcerative Colitis110.35 ± 92.70 mgs
Aquamin® - Healthy Subjects106.95 ± 86.68 mgs
Aquamin® - Subjects With Ulcerative Colitis51.60 ± 23.30 mgs
Aquamin® - Healthy Subjects829.14 ± 497.29 mgs
Aquamin® - Subjects With Ulcerative Colitis1277.08 ± 503.40 mgs
p-value0.322

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