GI Permeability Change in Response to Aquamin®
Phase 2
Completed
NCT04855799
| Condition | Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea |
|---|
| Phase | Phase 2 |
|---|
| Sponsor | James Varani |
|---|
| Status | Completed |
|---|
| Enrollment | 35 participants |
|---|
| Interventions | Aquamin |
|---|
| Start date | Nov 2, 2021 |
|---|
| Completion date | Mar 11, 2024 |
|---|
| Results posted | Jun 8, 2026 |
|---|
Summary
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people with ulcerative colitis (UC), Irritable Bowel Syndrome with diarrhea (IBS-D), and in healthy individuals.
Change in the Lactulose:Mannitol Ratio in Urine by Comparing Values at 90-days (Post-intervention) to Baseline (Pre-intervention) Levels.
Baseline (pre-intervention), 90 days (post-intervention)
Mannitol Levels in Urine Samples
90 days · mgs
| Aquamin® - Healthy Subjects | 68.54 ± 85.03 mgs |
|---|
| Aquamin® - Subjects With Ulcerative Colitis | 110.35 ± 92.70 mgs |
|---|
| Aquamin® - Healthy Subjects | 106.95 ± 86.68 mgs |
|---|
| Aquamin® - Subjects With Ulcerative Colitis | 51.60 ± 23.30 mgs |
|---|
| Aquamin® - Healthy Subjects | 829.14 ± 497.29 mgs |
|---|
| Aquamin® - Subjects With Ulcerative Colitis | 1277.08 ± 503.40 mgs |
|---|
Open in BENITIONS
View on ClinicalTrials.gov
Other trials for this condition
All trials
This page summarises publicly available data from ClinicalTrials.gov. It is not medical advice and not investment advice. Always consult a qualified healthcare professional.