BENITIONSClinical Trial Intelligence

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

2期 进行中(已停止招募) NCT02867592

适应症Adrenal Cortical Carcinoma, Alveolar Soft Part Sarcoma, Central Nervous System Neoplasm, Childhood Clear Cell Sarcoma of Soft Tissue
分期2期
申办方National Cancer Institute (NCI)
状态进行中(已停止招募)
受试者人数109 人
干预(药物)Cabozantinib, Cabozantinib S-malate, Pharmacological Study
开始日期2017年5月18日
完成日期2021年6月30日
结果公布日2022年11月28日

摘要

This phase II trial studies how well cabozantinib-s-malate works in treating younger patients with sarcomas, Wilms tumor, or other rare tumors that have come back, do not respond to therapy, or are newly diagnosed. Cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for tumor growth and tumor blood vessel growth.

Objective Response (Non-Osteosarcoma Strata)

Up to the first 6 cycles of therapy · Percentage of patients

Ewing's Sarcoma0 Percentage of patients
Rhabdomyosarcoma0 Percentage of patients
Non-Rhabdomyosarcoma Soft Tissue Sarcoma0 Percentage of patients
Wilms Tumor0 Percentage of patients
Rare Tumors13.04 Percentage of patients

Objective Response (Osteosarcoma Stratum)

Up to the first 6 cycles of therapy. · Percentage of patients

Osteosarcoma35.18 Percentage of patients

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

同一适应症的其他试验

全部试验

本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。