BENITIONSClinical Trial Intelligence

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Фаза 2 Идёт, набор закрыт NCT02867592

ЗаболеваниеAdrenal Cortical Carcinoma, Alveolar Soft Part Sarcoma, Central Nervous System Neoplasm, Childhood Clear Cell Sarcoma of Soft Tissue
ФазаФаза 2
СпонсорNational Cancer Institute (NCI)
СтатусИдёт, набор закрыт
Участники109 участн.
ВмешательствоCabozantinib, Cabozantinib S-malate, Pharmacological Study
Дата начала18.05.2017
Дата завершения30.06.2021
Публикация результатов28.11.2022

Кратко

This phase II trial studies how well cabozantinib-s-malate works in treating younger patients with sarcomas, Wilms tumor, or other rare tumors that have come back, do not respond to therapy, or are newly diagnosed. Cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for tumor growth and tumor blood vessel growth.

Objective Response (Non-Osteosarcoma Strata)

Up to the first 6 cycles of therapy · Percentage of patients

Ewing's Sarcoma0 Percentage of patients
Rhabdomyosarcoma0 Percentage of patients
Non-Rhabdomyosarcoma Soft Tissue Sarcoma0 Percentage of patients
Wilms Tumor0 Percentage of patients
Rare Tumors13.04 Percentage of patients

Objective Response (Osteosarcoma Stratum)

Up to the first 6 cycles of therapy. · Percentage of patients

Osteosarcoma35.18 Percentage of patients

Открыть в BENITIONS Открыть на ClinicalTrials.gov

Другие исследования по этому заболеванию

Все исследования

Страница обобщает открытые данные ClinicalTrials.gov. Это не медицинская и не инвестиционная рекомендация. Обратитесь к врачу.