Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer
| 대상 질환 | Small Cell Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8 |
|---|---|
| 임상 단계 | 2상 |
| 스폰서 | Wake Forest University Health Sciences |
| 상태 | 조기 종료 |
| 참여자 수 | 14 명 |
| 중재(약물) | Gemcitabine, Nivolumab |
| 시작일 | 2018년 11월 7일 |
| 완료일 | 2020년 10월 7일 |
| 결과 공개일 | 2021년 11월 12일 |
요약
This phase II pilot trial studies how well gemcitabine and nivolumab work in treating participants with small cell lung cancer that has spread to other parts of the body after other treatments have failed. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving second-line gemcitabine and nivolumab may work better in treating participants with small cell lung cancer.
Number of Participants With Positive Responses to Therapy Per Response Evaluation Criteria in Solid Tumors (RECIST)
| Treatment (Gemcitabine, Nivolumab) | 1 Participants |
|---|---|
| Treatment (Gemcitabine, Nivolumab) | 11 Participants |
| Treatment (Gemcitabine, Nivolumab) | 2 Participants |
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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