BENITIONSClinical Trial Intelligence

Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer

2期 提前终止 NCT03662074

适应症Small Cell Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
分期2期
申办方Wake Forest University Health Sciences
状态提前终止
受试者人数14 人
干预(药物)Gemcitabine, Nivolumab
开始日期2018年11月7日
完成日期2020年10月7日
结果公布日2021年11月12日

摘要

This phase II pilot trial studies how well gemcitabine and nivolumab work in treating participants with small cell lung cancer that has spread to other parts of the body after other treatments have failed. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving second-line gemcitabine and nivolumab may work better in treating participants with small cell lung cancer.

Number of Participants With Positive Responses to Therapy Per Response Evaluation Criteria in Solid Tumors (RECIST)

Up to 8 weeks · Participants

Treatment (Gemcitabine, Nivolumab)1 Participants
Treatment (Gemcitabine, Nivolumab)11 Participants
Treatment (Gemcitabine, Nivolumab)2 Participants

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。