Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer
| 対象疾患 | Small Cell Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8 |
|---|---|
| 相 | 第2相 |
| スポンサー | Wake Forest University Health Sciences |
| ステータス | 早期終了 |
| 参加者数 | 14 名 |
| 介入(薬剤) | Gemcitabine, Nivolumab |
| 開始日 | 2018年11月7日 |
| 完了日 | 2020年10月7日 |
| 結果公開日 | 2021年11月12日 |
概要
This phase II pilot trial studies how well gemcitabine and nivolumab work in treating participants with small cell lung cancer that has spread to other parts of the body after other treatments have failed. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving second-line gemcitabine and nivolumab may work better in treating participants with small cell lung cancer.
Number of Participants With Positive Responses to Therapy Per Response Evaluation Criteria in Solid Tumors (RECIST)
| Treatment (Gemcitabine, Nivolumab) | 1 Participants |
|---|---|
| Treatment (Gemcitabine, Nivolumab) | 11 Participants |
| Treatment (Gemcitabine, Nivolumab) | 2 Participants |
BENITIONS で見る ClinicalTrials.gov の原文を見る
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