BENITIONSClinical Trial Intelligence

Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)

第2相 完了 NCT06482112

対象疾患Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-alcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease, Liver Disease
第2相
スポンサーMerck Sharp & Dohme LLC
ステータス完了
参加者数124 名
介入(薬剤)Efinopegdutide
開始日2024年7月29日
完了日2025年6月27日
結果公開日2026年6月1日

概要

This study will evaluate the effect of efinopegdutide administration once every 2 weeks (Q2W) versus once weekly (Q1W) on mean relative reduction from baseline in liver fat content (LFC) after 28 weeks, as well as the safety and tolerability of the different regimens of efinopegdutide.

Mean Relative Reduction From Baseline in Liver Fat Content at Week 28

Baseline and Week 28 · Percent Reduction

Efinopegdutide Q1W 10 mg67.8 Percent Reduction
Efinopegdutide Q2W 10 mg54.4 Percent Reduction
Efinopegdutide Q2W 15 mg42.1 Percent Reduction

Percentage of Participants Who Experienced an Adverse Event (AE)

Up to Week 32 · Percentage of participants

Efinopegdutide Q1W 10 mg83.3 Percentage of participants
Efinopegdutide Q2W 10 mg82.1 Percentage of participants
Efinopegdutide Q2W 15 mg85.7 Percentage of participants

Percentage of Participants Who Discontinued Study Intervention Due to an AE

Up to Week 28 · Percentage of participants

Efinopegdutide Q1W 10 mg7.1 Percentage of participants
Efinopegdutide Q2W 10 mg5.1 Percentage of participants
Efinopegdutide Q2W 15 mg9.5 Percentage of participants

BENITIONS で見る ClinicalTrials.gov の原文を見る

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すべての治験

このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。