Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors
第3相
実施中(募集終了)
NCT03375320
| 対象疾患 | Functioning Pancreatic Neuroendocrine Tumor, Intermediate Grade Lung Neuroendocrine Neoplasm, Locally Advanced Digestive System Neuroendocrine Neoplasm, Locally Advanced Digestive System Neuroendocrine Tumor G1 |
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| 相 | 第3相 |
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| スポンサー | National Cancer Institute (NCI) |
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| ステータス | 実施中(募集終了) |
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| 参加者数 | 298 名 |
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| 介入(薬剤) | Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging, Placebo Administration |
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| 開始日 | 2018年10月26日 |
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| 完了日 | 2023年8月23日 |
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| 結果公開日 | 2024年10月16日 |
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概要
This phase III trial studies cabozantinib to see how well it works compared with placebo in treating patients with neuroendocrine or carcinoid tumors that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Cabozantinib is a chemotherapy drug known as a tyrosine kinase inhibitor, and it targets specific tyrosine kinase receptors, that when blocked, may slow tumor growth.
Progression-free Survival (PFS)
36 months · months
| Arm Ia (Cabozantinib S-malate, Extra-pancreatic NET Cohort [epNET]) | 8.4 months |
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| Arm IIa (Placebo, Extra-pancreatic NET Cohort [epNET]) | 3.9 months |
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| Arm Ib (Cabozantinib S-malate, Pancreatic NET Cohort [pNET]) | 13.8 months |
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| Arm IIb (Placebo, Pancreatic NET Cohort [pNET]) | 4.4 months |
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BENITIONS で見る
ClinicalTrials.gov の原文を見る
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このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。