BENITIONSClinical Trial Intelligence

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

3期 进行中(已停止招募) NCT05197049

适应症Crohn Disease
分期3期
申办方Janssen Research & Development, LLC
状态进行中(已停止招募)
受试者人数350 人
干预(药物)Guselkumab Dose 1, Guselkumab Dose 2, Guselkumab Dose 3
开始日期2022年1月19日
完成日期2023年7月4日
结果公布日2025年2月21日

摘要

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with Crohn's disease.

Percentage of Participants Who Achieved Clinical Remission at Week 12

At Week 12 · Percentage of participants

Placebo21.4 Percentage of participants
Combined: Guselkumab 400 mg56.1 Percentage of participants
p-value< 0.001
Adjusted treatment difference:percentage34.9 (95% CI 25.1–44.6)

Percentage of Participants Who Achieved Endoscopic Response at Week 12

At Week 12 · Percentage of participants

Placebo21.4 Percentage of participants
Combined: Guselkumab 400 mg41.3 Percentage of participants
p-value< 0.001
Adjusted treatment difference:percentage19.9 (95% CI 10.2–29.6)

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。