BENITIONSClinical Trial Intelligence

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

不适用 已完成 NCT03029884

适应症Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
分期不适用
申办方Prasad Shirvalkar, MD, PhD
状态已完成
受试者人数4 人
干预(药物)Open-Loop DBS, Sham Stimulation, Closed-Loop DBS
开始日期2017年10月28日
完成日期2023年9月30日
结果公布日2023年11月22日

摘要

Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief. A "one-size-fits-all" approach of continuous, 24/7 brain stimulation has helped patients with some movement disorders, but the key to reducing pain may be the activation of stimulation only when needed, as this may help keep the brain from adapting to stimulation effects. By expanding the technological capabilities of an investigative brain stimulation device, the investigators will enable the delivery of stimulation only when pain signals in the brain are high, and then test whether this more personalized stimulation leads to reliable symptom relief for chronic pain patients over extended periods of time.

Visual Analog Score

2 years · units on a scale (millimeters)

Inactive DBS Run in Period76 units on a scale (millimeters)
Open Loop DBS74 units on a scale (millimeters)
Closed Loop DBS75 units on a scale (millimeters)
Sham75 units on a scale (millimeters)

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。