Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
| 대상 질환 | Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries |
|---|---|
| 임상 단계 | 단계 해당 없음 |
| 스폰서 | Prasad Shirvalkar, MD, PhD |
| 상태 | 완료 |
| 참여자 수 | 4 명 |
| 중재(약물) | Open-Loop DBS, Sham Stimulation, Closed-Loop DBS |
| 시작일 | 2017년 10월 28일 |
| 완료일 | 2023년 9월 30일 |
| 결과 공개일 | 2023년 11월 22일 |
요약
Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief. A "one-size-fits-all" approach of continuous, 24/7 brain stimulation has helped patients with some movement disorders, but the key to reducing pain may be the activation of stimulation only when needed, as this may help keep the brain from adapting to stimulation effects. By expanding the technological capabilities of an investigative brain stimulation device, the investigators will enable the delivery of stimulation only when pain signals in the brain are high, and then test whether this more personalized stimulation leads to reliable symptom relief for chronic pain patients over extended periods of time.
Visual Analog Score
| Inactive DBS Run in Period | 76 units on a scale (millimeters) |
|---|---|
| Open Loop DBS | 74 units on a scale (millimeters) |
| Closed Loop DBS | 75 units on a scale (millimeters) |
| Sham | 75 units on a scale (millimeters) |
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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