BENITIONSClinical Trial Intelligence

Women's Health Initiative Strong and Healthy Study

不适用 已完成 NCT02425345

适应症Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
分期不适用
申办方Fred Hutchinson Cancer Center
状态已完成
受试者人数49,331 人
干预(药物)Physical Activity
开始日期2015年4月2日
完成日期2024年12月31日
结果公布日2026年5月13日

摘要

The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to \~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise \& Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.

Cardiovascular Events (Composite Myocardial Infarction, Stroke, Cardiovascular Mortality

median 8.7 years · Participants

Physical Activity Intervention5231 Participants
Usual Activity Control5324 Participants
p-value0.49
Hazard Ratio (HR)0.99 (95% CI 0.95–1.02)

Physical Function (Physical Function Score From Self-report, RAND-36)

Annually each year of the 9 years of the trial. The single value for this Outcome is based on the average of all collected measurements. · Score

Physical Activity Intervention59.73 ± 26.76 Score
Usual Activity Control58.73 ± 26.82 Score
p-value<0.001
Mean Difference (Final Values)0.91 (95% CI 0.46–1.37)

Non-Cardiovascular Disease Mortality

median 8.7 years · Participants

Physical Activity Intervention6336 Participants
Usual Activity Control6310 Participants
p-value0.85
Hazard Ratio (HR)1.00 (95% CI 0.97–1.04)

在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。