Women's Health Initiative Strong and Healthy Study
不适用
已完成
NCT02425345
| 适应症 | Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures |
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| 分期 | 不适用 |
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| 申办方 | Fred Hutchinson Cancer Center |
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| 状态 | 已完成 |
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| 受试者人数 | 49,331 人 |
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| 干预(药物) | Physical Activity |
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| 开始日期 | 2015年4月2日 |
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| 完成日期 | 2024年12月31日 |
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| 结果公布日 | 2026年5月13日 |
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摘要
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to \~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise \& Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.
Cardiovascular Events (Composite Myocardial Infarction, Stroke, Cardiovascular Mortality
median 8.7 years · Participants
| Physical Activity Intervention | 5231 Participants |
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| Usual Activity Control | 5324 Participants |
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| p-value | 0.49 |
| Hazard Ratio (HR) | 0.99 (95% CI 0.95–1.02) |
Physical Function (Physical Function Score From Self-report, RAND-36)
Annually each year of the 9 years of the trial. The single value for this Outcome is based on the average of all collected measurements. · Score
| Physical Activity Intervention | 59.73 ± 26.76 Score |
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| Usual Activity Control | 58.73 ± 26.82 Score |
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| p-value | <0.001 |
| Mean Difference (Final Values) | 0.91 (95% CI 0.46–1.37) |
Non-Cardiovascular Disease Mortality
median 8.7 years · Participants
| Physical Activity Intervention | 6336 Participants |
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| Usual Activity Control | 6310 Participants |
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| p-value | 0.85 |
| Hazard Ratio (HR) | 1.00 (95% CI 0.97–1.04) |
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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。