BENITIONSClinical Trial Intelligence

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

Не применимо Завершено NCT03029884

ЗаболеваниеChronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
ФазаНе применимо
СпонсорPrasad Shirvalkar, MD, PhD
СтатусЗавершено
Участники4 участн.
ВмешательствоOpen-Loop DBS, Sham Stimulation, Closed-Loop DBS
Дата начала28.10.2017
Дата завершения30.09.2023
Публикация результатов22.11.2023

Кратко

Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief. A "one-size-fits-all" approach of continuous, 24/7 brain stimulation has helped patients with some movement disorders, but the key to reducing pain may be the activation of stimulation only when needed, as this may help keep the brain from adapting to stimulation effects. By expanding the technological capabilities of an investigative brain stimulation device, the investigators will enable the delivery of stimulation only when pain signals in the brain are high, and then test whether this more personalized stimulation leads to reliable symptom relief for chronic pain patients over extended periods of time.

Visual Analog Score

2 years · units on a scale (millimeters)

Inactive DBS Run in Period76 units on a scale (millimeters)
Open Loop DBS74 units on a scale (millimeters)
Closed Loop DBS75 units on a scale (millimeters)
Sham75 units on a scale (millimeters)

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