Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
| 対象疾患 | Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries |
|---|---|
| 相 | 該当なし |
| スポンサー | Prasad Shirvalkar, MD, PhD |
| ステータス | 完了 |
| 参加者数 | 4 名 |
| 介入（薬剤） | Open-Loop DBS, Sham Stimulation, Closed-Loop DBS |
| 開始日 | 2017年10月28日 |
| 完了日 | 2023年9月30日 |
| 結果公開日 | 2023年11月22日 |
概要
Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief. A "one-size-fits-all" approach of continuous, 24/7 brain stimulation has helped patients with some movement disorders, but the key to reducing pain may be the activation of stimulation only when needed, as this may help keep the brain from adapting to stimulation effects. By expanding the technological capabilities of an investigative brain stimulation device, the investigators will enable the delivery of stimulation only when pain signals in the brain are high, and then test whether this more personalized stimulation leads to reliable symptom relief for chronic pain patients over extended periods of time.
Visual Analog Score
| Inactive DBS Run in Period | 76 units on a scale (millimeters) |
|---|---|
| Open Loop DBS | 74 units on a scale (millimeters) |
| Closed Loop DBS | 75 units on a scale (millimeters) |
| Sham | 75 units on a scale (millimeters) |
BENITIONS で見る ClinicalTrials.gov の原文を見る
同じ疾患の他の治験
- Women's Health Initiative Strong and Healthy Study — Fred Hutchinson Cancer Center
- Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic Stroke — Shionogi
- Zambia Stroke Unit Study — Johns Hopkins University
- Tracking Post-stroke Walking Improvements From the Clinic Into the Home — Western University of Health Sciences
- Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coord — Weill Medical College of Cornell University
- Safety and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic Stroke — Shionogi