BENITIONSClinical Trial Intelligence

Bridging the Childhood Epilepsy Treatment Gap in Africa

단계 해당 없음 완료 NCT04290975

대상 질환Epilepsy
임상 단계단계 해당 없음
스폰서Vanderbilt University Medical Center
상태완료
참여자 수1,672 명
중재(약물)Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC)
시작일2020년 6월 16일
완료일2024년 5월 31일
결과 공개일2026년 2월 20일

요약

About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel intervention shifting childhood epilepsy care to epilepsy-trained community health extension workers in an effort to close the epilepsy treatment gap. This research will provide information to help extend epilepsy treatment to children in LMICs and worldwide who suffer from untreated seizures.

Percentage Seizure-free for 6 Months, or Longer, Measured at 24 Months After Enrollment

Outcome measured 18 months to 24 months after enrollment · Participants

Task-shifted Epilepsy Care Arm (TSC)371 Participants
Enhanced Usual Epilepsy Care Arm (EUC)299 Participants
p-value0.11
Odds Ratio (OR)1.37 (95% CI 0.93–2.02)

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