Bridging the Childhood Epilepsy Treatment Gap in Africa
단계 해당 없음
완료
NCT04290975
| 대상 질환 | Epilepsy |
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| 임상 단계 | 단계 해당 없음 |
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| 스폰서 | Vanderbilt University Medical Center |
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| 상태 | 완료 |
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| 참여자 수 | 1,672 명 |
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| 중재(약물) | Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC) |
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| 시작일 | 2020년 6월 16일 |
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| 완료일 | 2024년 5월 31일 |
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| 결과 공개일 | 2026년 2월 20일 |
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요약
About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel intervention shifting childhood epilepsy care to epilepsy-trained community health extension workers in an effort to close the epilepsy treatment gap. This research will provide information to help extend epilepsy treatment to children in LMICs and worldwide who suffer from untreated seizures.
Percentage Seizure-free for 6 Months, or Longer, Measured at 24 Months After Enrollment
Outcome measured 18 months to 24 months after enrollment · Participants
| Task-shifted Epilepsy Care Arm (TSC) | 371 Participants |
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| Enhanced Usual Epilepsy Care Arm (EUC) | 299 Participants |
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| p-value | 0.11 |
| Odds Ratio (OR) | 1.37 (95% CI 0.93–2.02) |
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