Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
| 대상 질환 | Transformed Migraine, Chronic Daily Headache |
|---|---|
| 임상 단계 | 4상 |
| 스폰서 | Rutgers, The State University of New Jersey |
| 상태 | 조기 종료 |
| 참여자 수 | 10 명 |
| 중재(약물) | SPG Block with 5% Lidocaine gel, Amitriptyline |
| 시작일 | 2014년 5월 |
| 완료일 | 2020년 3월 16일 |
| 결과 공개일 | 2021년 12월 29일 |
요약
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil. Subjects will be randomized into one of two treatment groups to compare the safety and efficacy of the therapies. Subjects will recieve either sphenopalatine ganglion nerve block with 5% lidocaine gel into the nasopharynx or medical management with traditional antidepressants, Elavil, to produce a reduction in the frequency and severity of the headache. We propose that there will be a difference in the outcomes when comparing the two methods of treating transformed migraines and that one research arm will result in more patient satisfaction and greater efficacy in the treatment of subjects
Number of Daily Headaches
| Amitriptyline / Elavil | 20.5 ± 0.5 Number of Daily Headaches |
|---|---|
| SPG Nerve Block With Lidocaine 5% Gel | 13.4 ± 10.4 Number of Daily Headaches |
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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