BENITIONSClinical Trial Intelligence

Bridging the Childhood Epilepsy Treatment Gap in Africa

該当なし 完了 NCT04290975

対象疾患Epilepsy
該当なし
スポンサーVanderbilt University Medical Center
ステータス完了
参加者数1,672 名
介入(薬剤)Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC)
開始日2020年6月16日
完了日2024年5月31日
結果公開日2026年2月20日

概要

About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel intervention shifting childhood epilepsy care to epilepsy-trained community health extension workers in an effort to close the epilepsy treatment gap. This research will provide information to help extend epilepsy treatment to children in LMICs and worldwide who suffer from untreated seizures.

Percentage Seizure-free for 6 Months, or Longer, Measured at 24 Months After Enrollment

Outcome measured 18 months to 24 months after enrollment · Participants

Task-shifted Epilepsy Care Arm (TSC)371 Participants
Enhanced Usual Epilepsy Care Arm (EUC)299 Participants
p-value0.11
Odds Ratio (OR)1.37 (95% CI 0.93–2.02)

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