Bridging the Childhood Epilepsy Treatment Gap in Africa
不适用
已完成
NCT04290975
| 适应症 | Epilepsy |
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| 分期 | 不适用 |
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| 申办方 | Vanderbilt University Medical Center |
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| 状态 | 已完成 |
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| 受试者人数 | 1,672 人 |
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| 干预(药物) | Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC) |
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| 开始日期 | 2020年6月16日 |
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| 完成日期 | 2024年5月31日 |
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| 结果公布日 | 2026年2月20日 |
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摘要
About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel intervention shifting childhood epilepsy care to epilepsy-trained community health extension workers in an effort to close the epilepsy treatment gap. This research will provide information to help extend epilepsy treatment to children in LMICs and worldwide who suffer from untreated seizures.
Percentage Seizure-free for 6 Months, or Longer, Measured at 24 Months After Enrollment
Outcome measured 18 months to 24 months after enrollment · Participants
| Task-shifted Epilepsy Care Arm (TSC) | 371 Participants |
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| Enhanced Usual Epilepsy Care Arm (EUC) | 299 Participants |
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| p-value | 0.11 |
| Odds Ratio (OR) | 1.37 (95% CI 0.93–2.02) |
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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。