Bridging the Childhood Epilepsy Treatment Gap in Africa
Не применимо
Завершено
NCT04290975
| Заболевание | Epilepsy |
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| Фаза | Не применимо |
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| Спонсор | Vanderbilt University Medical Center |
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| Статус | Завершено |
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| Участники | 1,672 участн. |
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| Вмешательство | Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC) |
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| Дата начала | 16.06.2020 |
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| Дата завершения | 31.05.2024 |
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| Публикация результатов | 20.02.2026 |
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Кратко
About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel intervention shifting childhood epilepsy care to epilepsy-trained community health extension workers in an effort to close the epilepsy treatment gap. This research will provide information to help extend epilepsy treatment to children in LMICs and worldwide who suffer from untreated seizures.
Percentage Seizure-free for 6 Months, or Longer, Measured at 24 Months After Enrollment
Outcome measured 18 months to 24 months after enrollment · Participants
| Task-shifted Epilepsy Care Arm (TSC) | 371 Participants |
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| Enhanced Usual Epilepsy Care Arm (EUC) | 299 Participants |
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| p-value | 0.11 |
| Odds Ratio (OR) | 1.37 (95% CI 0.93–2.02) |
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