Accelerated rTMS for Post-Stroke Apathy
第1相
完了
NCT05878457
| 対象疾患 | Apathy, Stroke Sequelae, Stroke or TIA, Stroke/Brain Attack |
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| 相 | 第1相 |
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| スポンサー | Medical University of South Carolina |
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| ステータス | 完了 |
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| 参加者数 | 21 名 |
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| 介入(薬剤) | MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System |
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| 開始日 | 2023年12月1日 |
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| 完了日 | 2025年4月30日 |
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| 結果公開日 | 2026年7月10日 |
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概要
This pilot study will investigate the safety, feasibility, tolerability, and preliminary efficacy of accelerated high-dose repetitive transcranial magnetic stimulation (rTMS) targeting the medial prefrontal cortex (mPFC) to address apathy symptoms in individuals with chronic stroke.
Change in Apathy Symptoms, as Measured by the Lille Apathy Rating Scale (LARS) Compared to Baseline
Pre-treatment, immediately post-treatment, and at one-month follow-up · scores on a scale
| Repetitive Transcranial Magnetic Stimulation | -20.86 ± 8.56 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | -23.36 ± 5.89 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | -26.86 ± 5.04 scores on a scale |
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Treatment-Emergent Adverse Events and Side Effects as Assessed by Intermittent Theta Burst Stimulation Review of Systems (iTBS ROS)
Across the 3 rTMS treatment days · scores on a scale
| Repetitive Transcranial Magnetic Stimulation | 0 ± 0 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 1.21 ± 1.72 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 0.71 ± 1.44 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 0.00 ± 0.00 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 1.21 ± 1.72 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 0.00 ± 0.00 scores on a scale |
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Change in Global Cognition, as Measured by the Montreal Cognitive Assessment (MoCA) Compared to Baseline
Pre-treatment, immediately post-treatment, and at one-month follow-up · scores on a scale
| Repetitive Transcranial Magnetic Stimulation | 24.50 ± 3.23 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 25.00 ± 3.67 scores on a scale |
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| Repetitive Transcranial Magnetic Stimulation | 25.20 ± 3.56 scores on a scale |
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BENITIONS で見る
ClinicalTrials.gov の原文を見る
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このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。