BENITIONSClinical Trial Intelligence

Women's Health Initiative Strong and Healthy Study

該当なし 完了 NCT02425345

対象疾患Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
該当なし
スポンサーFred Hutchinson Cancer Center
ステータス完了
参加者数49,331 名
介入(薬剤)Physical Activity
開始日2015年4月2日
完了日2024年12月31日
結果公開日2026年5月13日

概要

The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to \~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise \& Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.

Cardiovascular Events (Composite Myocardial Infarction, Stroke, Cardiovascular Mortality

median 8.7 years · Participants

Physical Activity Intervention5231 Participants
Usual Activity Control5324 Participants
p-value0.49
Hazard Ratio (HR)0.99 (95% CI 0.95–1.02)

Physical Function (Physical Function Score From Self-report, RAND-36)

Annually each year of the 9 years of the trial. The single value for this Outcome is based on the average of all collected measurements. · Score

Physical Activity Intervention59.73 ± 26.76 Score
Usual Activity Control58.73 ± 26.82 Score
p-value<0.001
Mean Difference (Final Values)0.91 (95% CI 0.46–1.37)

Non-Cardiovascular Disease Mortality

median 8.7 years · Participants

Physical Activity Intervention6336 Participants
Usual Activity Control6310 Participants
p-value0.85
Hazard Ratio (HR)1.00 (95% CI 0.97–1.04)

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