BENITIONSClinical Trial Intelligence

Exploratory Open Label Study for Development of a Method To Detect Dendritic Cells

該当なし 完了 NCT05482867

対象疾患Probable Alzheimer's Disease
該当なし
スポンサーMindImmune Therapeutics, Inc.
ステータス完了
参加者数46 名
開始日2022年11月28日
完了日2024年8月7日
結果公開日2026年7月8日

概要

This is a proof-of-concept study designed to confirm that human phagocytic cells can be labeled with the near-infrared dye indocyanine green (ICG) and the presence of the labeled cells 48 hours later in cerebral cortex can be inferred using near infrared spectroscopy (NIRS).

Treatment Emergent Adverse Events (TEAEs)

Dosing (Day 0) through Telephone Follow-up (Day 16) · participants

Cohort 13 participants
Cohort 26 participants
Cohort 2A1 participants
Cohort 3A,3 participants
Cohort 37 participants
Cohort4,2 participants

Electrocardiogram Results

Screening, Day 0 and Day 2 · participants

Cohort 12 participants
Cohort 22 participants
Cohort 2A0 participants
Cohort 3A,1 participants
Cohort 34 participants
Cohort 4,1 participants

Mean ICG Concentrations

Post Dosing time points: at 60 mins, 120 mins, 150 mins, 240 mins and 48 hours · ng/mLs

Cohort 12743.76 ng/mLs
Cohort 23388.33 ng/mLs
Cohort 34377.45 ng/mLs
Cohort 2A2591.10 ng/mLs
Cohort 3A,5032.67 ng/mLs
Cohort4,3181.98 ng/mLs

BENITIONS で見る ClinicalTrials.gov の原文を見る

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このページは ClinicalTrials.gov の公開データをまとめたものです。医学的助言ではなく、投資助言でもありません。必ず専門医にご相談ください。