A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis
3期
进行中(已停止招募)
NCT06095115
| 适应症 | Plaque Psoriasis |
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| 分期 | 3期 |
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| 申办方 | Janssen Research & Development, LLC |
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| 状态 | 进行中(已停止招募) |
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| 受试者人数 | 684 人 |
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| 干预(药物) | JNJ-77242113 |
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| 开始日期 | 2023年10月12日 |
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| 完成日期 | 2024年7月29日 |
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| 结果公布日 | 2026年6月1日 |
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摘要
The purpose of this study is see how effective is JNJ-77242113 in participants with moderate to severe plaque psoriasis.
Percentage of Participants Who Achieved an Investigator's Global Assessment (IGA) Score of 0 or 1 and Greater Than or Equal to (>=) 2-Grade Improvement From Baseline at Week 16
Week 16 · Percentage of Participants
| Placebo to JNJ-77242113 200 mg | 8.3 Percentage of Participants |
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| JNJ-77242113 200 mg | 64.7 Percentage of Participants |
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| p-value | <0.001 |
| Treatment difference | 56.4 (95% CI 50.4–61.7) |
Percentage of Participants Who Achieved Psoriasis Area and Severity Index (PASI) 90 Response at Week 16
Week 16 · Percentage of participants
| Placebo to JNJ-77242113 200 mg | 4.4 Percentage of participants |
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| JNJ-77242113 200 mg | 49.6 Percentage of participants |
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| p-value | <0.001 |
| Treatment difference | 45.1 (95% CI 39.5–50.4) |
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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。