Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
| 适应症 | Malignant Solid Neoplasm, Recurrent Adrenal Gland Pheochromocytoma, Recurrent Ectomesenchymoma, Recurrent Ependymoma |
|---|---|
| 分期 | 2期 |
| 申办方 | National Cancer Institute (NCI) |
| 状态 | 进行中（已停止招募） |
| 受试者人数 | 5 人 |
| 干预（药物） | Tipifarnib |
| 开始日期 | 2020年10月13日 |
| 完成日期 | 2024年3月31日 |
| 结果公布日 | 2025年6月3日 |
摘要
This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have recurred or spread to other places in the body (advanced), lymphoma, or histiocytic disorders, that have a genetic alteration in the gene HRAS. Tipifarnib may block the growth of cancer cells that have specific genetic changes in a gene called HRAS and may reduce tumor size.
Objective Response Rate (Complete Response + Partial Response) in Pediatric Patients Treated With Tipifarnib
| Treatment (Tipifarnib) | 0 percentage of patients |
|---|
在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文
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