BENITIONSClinical Trial Intelligence

Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma

1期 已完成 NCT01024231

适应症Malignant Melanoma
分期1期
申办方Bristol-Myers Squibb
状态已完成
受试者人数127 人
干预(药物)BMS-936558 (MDX1106-04), Ipilimumab
开始日期2009年12月14日
完成日期2014年2月4日
结果公布日2021年3月22日

摘要

The purpose of this study is to determine the safety and tolerability of treatment with BMS-936558 (MDX-1106) in combination with Ipilimumab (BMS-734016) when given at the same time or as a sequenced regimen in subjects with unresectable Stage III or Stage IV malignant melanoma (MEL)

Number of Participants With an Adverse Event (AE)

Up to 3 years · Participants

Cohort 114 Participants
Cohort 217 Participants
Cohort 2a16 Participants
Cohort 36 Participants
Any BMS and Ipi Combo53 Participants
Cohort 617 Participants

Number of Participants With a Serious Adverse Event (AE)

Up to 3 years · Participants

Cohort 110 Participants
Cohort 215 Participants
Cohort 2a10 Participants
Cohort 35 Participants
Any BMS and Ipi Combo40 Participants
Cohort 69 Participants

Number of Participants With an Adverse Event (AE) Which Lead to Discontinuation

Up to 3 years · Participants

Cohort 12 Participants
Cohort 28 Participants
Cohort 2a5 Participants
Cohort 31 Participants
Any BMS and Ipi Combo16 Participants
Cohort 65 Participants

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本页整理自 ClinicalTrials.gov 的公开数据,不构成医疗建议,也不构成投资建议。请务必咨询专业医师。