Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Фаза 2 Идёт, набор закрыт NCT04284774

Кратко

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have recurred or spread to other places in the body (advanced), lymphoma, or histiocytic disorders, that have a genetic alteration in the gene HRAS. Tipifarnib may block the growth of cancer cells that have specific genetic changes in a gene called HRAS and may reduce tumor size.

Objective Response Rate (Complete Response + Partial Response) in Pediatric Patients Treated With Tipifarnib

Up to 2 years from study entry · percentage of patients

Открыть в BENITIONS Открыть на ClinicalTrials.gov

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Все исследования