Dose Finding Study of MCI-186 in Acute Ischemic Stroke
| 适应症 | Acute Ischemic Stroke |
|---|---|
| 分期 | 2期 |
| 申办方 | Shionogi |
| 状态 | 提前终止 |
| 受试者人数 | 17 人 |
| 干预（药物） | Continuous infusion high-dose MCI-186, Continuous infusion low-dose MCI-186, Continuous infusion placebo, Approved dosing regimen MCI-186, Approved dosing regimen placebo |
| 开始日期 | 2017年11月17日 |
| 完成日期 | 2018年5月14日 |
| 结果公布日 | 2025年1月9日 |
摘要
To investigate the efficacy and safety of MCI-186 (bolus followed by continuous infusion) in acute ischemic stroke patients through a double-blind, parallel-group comparison with the existing MCI-186 dosing regimen (administration twice daily for 14 days) as the control.
Number of Participants With National Institutes of Health Stroke Scale (NIHSS) Score Improved.
| Continuous Infusion High-dose Group (Group H) | 0 Participants |
|---|---|
| Continuous Infusion Low-dose Group (Group L) | 0 Participants |
| Approved Dosing Regimen Group (Control Group) | 0 Participants |
| Continuous Infusion High-dose Group (Group H) | 2 Participants |
| Continuous Infusion Low-dose Group (Group L) | 0 Participants |
| Approved Dosing Regimen Group (Control Group) | 1 Participants |
在 BENITIONS 中查看 查看 ClinicalTrials.gov 原文
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- Zambia Stroke Unit Study — Johns Hopkins University
- Tracking Post-stroke Walking Improvements From the Clinic Into the Home — Western University of Health Sciences
- Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coord — Weill Medical College of Cornell University