Dose Finding Study of MCI-186 in Acute Ischemic Stroke
| Condition | Acute Ischemic Stroke |
|---|---|
| Phase | Phase 2 |
| Sponsor | Shionogi |
| Status | Terminated |
| Enrollment | 17 participants |
| Interventions | Continuous infusion high-dose MCI-186, Continuous infusion low-dose MCI-186, Continuous infusion placebo, Approved dosing regimen MCI-186, Approved dosing regimen placebo |
| Start date | Nov 17, 2017 |
| Completion date | May 14, 2018 |
| Results posted | Jan 9, 2025 |
Summary
To investigate the efficacy and safety of MCI-186 (bolus followed by continuous infusion) in acute ischemic stroke patients through a double-blind, parallel-group comparison with the existing MCI-186 dosing regimen (administration twice daily for 14 days) as the control.
Number of Participants With National Institutes of Health Stroke Scale (NIHSS) Score Improved.
| Continuous Infusion High-dose Group (Group H) | 0 Participants |
|---|---|
| Continuous Infusion Low-dose Group (Group L) | 0 Participants |
| Approved Dosing Regimen Group (Control Group) | 0 Participants |
| Continuous Infusion High-dose Group (Group H) | 2 Participants |
| Continuous Infusion Low-dose Group (Group L) | 0 Participants |
| Approved Dosing Regimen Group (Control Group) | 1 Participants |
Open in BENITIONS View on ClinicalTrials.gov
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- Zambia Stroke Unit Study — Johns Hopkins University
- Tracking Post-stroke Walking Improvements From the Clinic Into the Home — Western University of Health Sciences
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