Women's Health Initiative Strong and Healthy Study
N/A
Completed
NCT02425345
| Condition | Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures |
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| Phase | N/A |
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| Sponsor | Fred Hutchinson Cancer Center |
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| Status | Completed |
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| Enrollment | 49,331 participants |
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| Interventions | Physical Activity |
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| Start date | Apr 2, 2015 |
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| Completion date | Dec 31, 2024 |
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| Results posted | May 13, 2026 |
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Summary
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to \~25,000 older U.S. women expected to consent. It includes the National Institute of Aging (NIA) Go4Life® Exercise \& Physical Activity materials 3 and WHISH developed targeted materials based on Go4Life® to provide inspirational tips and recommendations about how to achieve nationally recommended levels of PA and overcome barriers to exercise, with a means for self-monitoring and setting personal goals. The intervention builds upon evidence-based behavioral science principles and intervention components that have proven to be effective in increasing PA in older women, with innovative adaptive approaches to tailoring the delivery to meet individual (personal) needs.
Cardiovascular Events (Composite Myocardial Infarction, Stroke, Cardiovascular Mortality
median 8.7 years · Participants
| Physical Activity Intervention | 5231 Participants |
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| Usual Activity Control | 5324 Participants |
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| p-value | 0.49 |
| Hazard Ratio (HR) | 0.99 (95% CI 0.95–1.02) |
Physical Function (Physical Function Score From Self-report, RAND-36)
Annually each year of the 9 years of the trial. The single value for this Outcome is based on the average of all collected measurements. · Score
| Physical Activity Intervention | 59.73 ± 26.76 Score |
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| Usual Activity Control | 58.73 ± 26.82 Score |
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| p-value | <0.001 |
| Mean Difference (Final Values) | 0.91 (95% CI 0.46–1.37) |
Non-Cardiovascular Disease Mortality
median 8.7 years · Participants
| Physical Activity Intervention | 6336 Participants |
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| Usual Activity Control | 6310 Participants |
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| p-value | 0.85 |
| Hazard Ratio (HR) | 1.00 (95% CI 0.97–1.04) |
Open in BENITIONS
View on ClinicalTrials.gov
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This page summarises publicly available data from ClinicalTrials.gov. It is not medical advice and not investment advice. Always consult a qualified healthcare professional.