BENITIONSClinical Trial Intelligence

Long-Term Study (AtDvance) to Evaluate GSK1070806 in Atopic Dermatitis.

Phase 2 Terminated NCT06447506

ConditionDermatitis, Atopic
PhasePhase 2
SponsorGlaxoSmithKline
StatusTerminated
Enrollment79 participants
InterventionsGSK1070806
Start dateJun 5, 2024
Completion dateJul 29, 2025
Results postedJun 16, 2026

Summary

The study is designed to evaluate the long-term safety and efficacy of GSK1070806 in participants with moderate-to severe atopic dermatitis, who have completed phase 2b parent GSK atopic dermatitis (AtD) study (NCT05999799).

Number of Participants With Treatment Emergent Adverse Events (TEAEs)

Up to Week 59 · Participants

Placebo/Placebo1 Participants
Placebo/GSK1070806 Dose Level 411 Participants
GSK1070806 Dose Level 1/GSK1070806 Dose Level 10 Participants
GSK1070806 Dose Level 1/GSK1070806 Dose Level 46 Participants
GSK1070806 Dose Level 2/GSK1070806 Dose Level 23 Participants
GSK1070806 Dose Level 2/GSK1070806 Dose Level 44 Participants

Number of Participants With TEAEs Leading to Permanent Discontinuation

Up to Week 59 · Participants

Placebo/Placebo1 Participants
Placebo/GSK1070806 Dose Level 40 Participants
GSK1070806 Dose Level 1/GSK1070806 Dose Level 10 Participants
GSK1070806 Dose Level 1/GSK1070806 Dose Level 40 Participants
GSK1070806 Dose Level 2/GSK1070806 Dose Level 20 Participants
GSK1070806 Dose Level 2/GSK1070806 Dose Level 40 Participants

Number of Participants With Serious Adverse Events (SAEs)

Up to Week 59 · Participants

Placebo/Placebo1 Participants
Placebo/GSK1070806 Dose Level 40 Participants
GSK1070806 Dose Level 1/GSK1070806 Dose Level 10 Participants
GSK1070806 Dose Level 1/GSK1070806 Dose Level 41 Participants
GSK1070806 Dose Level 2/GSK1070806 Dose Level 20 Participants
GSK1070806 Dose Level 2/GSK1070806 Dose Level 40 Participants

Open in BENITIONS View on ClinicalTrials.gov

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