BENITIONSClinical Trial Intelligence

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States

Phase 4 Completed NCT05329194

ConditionAsthma
PhasePhase 4
SponsorAstraZeneca
StatusCompleted
Enrollment286 participants
InterventionsTezepelumab
Start dateApr 29, 2022
Completion dateOct 1, 2025
Results postedJul 16, 2026

Summary

To asses effectiveness and safety of tezepelumab in adult and adolescent participants with severe asthma including several under-studied populations in the United States.

Annualized Asthma Exacerbation Rate (AAER)

Baseline period (Week -52 to Week 0), Study period (Week 0 to Week 52) · Adjusted rate (exacerbations per year)

Tezepelumab2.8783 ± 2.69 Adjusted rate (exacerbations per year)
Tezepelumab0.8665 ± 0.71 Adjusted rate (exacerbations per year)

Open in BENITIONS View on ClinicalTrials.gov

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