BENITIONSClinical Trial Intelligence

Administration of ARS-1 or Albuterol in Subjects With Persistent Asthma

Phase 2 Completed NCT05363670

ConditionAsthma
PhasePhase 2
SponsorARS Pharmaceuticals, Inc.
StatusCompleted
Enrollment18 participants
InterventionsARS-1 1 mg, Albuterol MDI, ARS-1 2mg
Start dateJul 28, 2022
Completion dateFeb 2, 2024
Results postedJul 14, 2026

Summary

ARS-1 is being developed for patients as a needleless alternative route of epinephrine administration for the management of refractory asthma symptoms.

Effect of ARS-1 Versus Albuterol and Placebo

From baseline (timepoints 0) to 1 hour · FEV1 L per hour

ARS-1 1mg0.150 ± 0.223 FEV1 L per hour
ARS-1 2mg0.233 ± 0.216 FEV1 L per hour
Placebo-0.002 ± 0.118 FEV1 L per hour
Albuterol0.378 ± 0.265 FEV1 L per hour

Open in BENITIONS View on ClinicalTrials.gov

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