Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)

Phase 2 Completed NCT04740307

Summary

The purpose of this study is to evaluate the safety and efficacy of fixed dose coformulated pembrolizumab/quavonlimab (MK-1308A) plus lenvatinib in a first line (1L) hepatocellular carcinoma (HCC) setting. No hypothesis testing will be performed.

Number of Participants With a Dose-Limiting Toxicity (DLT) in the Safety Lead-in Phase

3 weeks · Participants

Number of Participants With ≥1 Adverse Event (AE)

Up to approximately 44 months · Participants

Number of Participants With ≥1 Serious Adverse Event (SAE)

Up to approximately 44 months · Participants

Open in BENITIONS View on ClinicalTrials.gov

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