Predicting SSRI Efficacy in Veterans With PTSD

Phase 4 Terminated NCT04183205

Summary

This is a research study to examine the effectiveness of a brief screening method that may predict which people with posttraumatic stress disorder (PTSD) or depression are most likely to show a positive response to selective serotonin reuptake inhibitor (SSRI) medications. Participants will be recruited over approximately 5.25 years, until at least 94 participants complete the 17 week study.

Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) After 14 Weeks of the Medication Trial Predicted by Pretreatment LDAEP Slope (Calculated With P200 at the PZ Site) and Controlling for Baseline CAPS Score

CAPS score administered 14 weeks after starting the medication trial, controlling for baseline CAPS score · Scores on a scale

Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) After 14 Weeks of the Medication Trial as Predicted by Pretreatment LDAEP Slope (Calculated With P200 at the CZ Site) and Controlling for Baseline CAPS Score

CAPS score administered 14 weeks after starting the medication trial, controlling for baseline CAPS score · Scores on a scale

Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) After 14 Weeks of the Medication Trial as Predicted by Pretreatment LDAEP Slope (Calculated With P200 at the FZ Site) and Controlling for Baseline CAPS Score

CAPS score administered 14 weeks after starting the medication trial, controlling for baseline CAPS score · Scores on a scale

Open in BENITIONS View on ClinicalTrials.gov

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