BENITIONSClinical Trial Intelligence

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

Phase 3 Terminated NCT04064827

ConditionChronic Kidney Disease, Secondary Hyperparathyroidism
PhasePhase 3
SponsorAbbVie
StatusTerminated
Enrollment2 participants
InterventionsParicalcitol
Start dateSep 16, 2020
Completion dateJun 9, 2025
Results postedJun 15, 2026

Summary

The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of ages 0 to 9 years with SHPT associated with stage 5 CKD receiving Peritoneal Dialysis (PD) or Hemodialysis (HD). The 24-week study is divided into two 12-week dosing periods (Dosing Period 1 followed by Dosing Period 2).

Percentage of Participants Who Achieve Positive Response During Dosing Period 1

Up to Week 12 · percentage of participants

Participants Receiving Paricalcitol100 percentage of participants

Incidence of Hypercalcemia During Dosing Period 1

Up to Week 12 · Participants

Participants Receiving Paricalcitol0 Participants

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