BENITIONSClinical Trial Intelligence

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

Фаза 3 Прекращено NCT04064827

ЗаболеваниеChronic Kidney Disease, Secondary Hyperparathyroidism
ФазаФаза 3
СпонсорAbbVie
СтатусПрекращено
Участники2 участн.
ВмешательствоParicalcitol
Дата начала16.09.2020
Дата завершения9.06.2025
Публикация результатов15.06.2026

Кратко

The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of ages 0 to 9 years with SHPT associated with stage 5 CKD receiving Peritoneal Dialysis (PD) or Hemodialysis (HD). The 24-week study is divided into two 12-week dosing periods (Dosing Period 1 followed by Dosing Period 2).

Percentage of Participants Who Achieve Positive Response During Dosing Period 1

Up to Week 12 · percentage of participants

Participants Receiving Paricalcitol100 percentage of participants

Incidence of Hypercalcemia During Dosing Period 1

Up to Week 12 · Participants

Participants Receiving Paricalcitol0 Participants

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