A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis
| Заболевание | Dermatitis, Atopic |
|---|---|
| Фаза | Фаза 2 |
| Спонсор | GlaxoSmithKline |
| Статус | Прекращено |
| Участники | 161 участн. |
| Вмешательство | GSK1070806 |
| Дата начала | 16.11.2023 |
| Дата завершения | 23.07.2025 |
| Публикация результатов | 3.06.2026 |
Кратко
This study is parallel group, placebo-controlled dose-ranging study to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of GSK1070806 in adult participants with moderate to severe Atopic Dermatitis (AtD), who have previously been treated with medicated topical treatments or a biologic therapy.
Percent Change From Baseline (CFB) in Eczema Area and Severity Index (EASI) Score at Week 16
| Placebo | -44.53 ± 40.805 Percent Change |
|---|---|
| GSK1070806 Dose Level 1 | -42.86 ± 36.186 Percent Change |
| GSK1070806 Dose Level 2 | -69.95 ± 33.363 Percent Change |
| GSK1070806 Dose Level 3 | -41.49 ± 43.341 Percent Change |
| GSK1070806 Dose Level 4 | -58.08 ± 33.129 Percent Change |
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