A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis
| 대상 질환 | Dermatitis, Atopic |
|---|---|
| 임상 단계 | 2상 |
| 스폰서 | GlaxoSmithKline |
| 상태 | 조기 종료 |
| 참여자 수 | 161 명 |
| 중재(약물) | GSK1070806 |
| 시작일 | 2023년 11월 16일 |
| 완료일 | 2025년 7월 23일 |
| 결과 공개일 | 2026년 6월 3일 |
요약
This study is parallel group, placebo-controlled dose-ranging study to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of GSK1070806 in adult participants with moderate to severe Atopic Dermatitis (AtD), who have previously been treated with medicated topical treatments or a biologic therapy.
Percent Change From Baseline (CFB) in Eczema Area and Severity Index (EASI) Score at Week 16
| Placebo | -44.53 ± 40.805 Percent Change |
|---|---|
| GSK1070806 Dose Level 1 | -42.86 ± 36.186 Percent Change |
| GSK1070806 Dose Level 2 | -69.95 ± 33.363 Percent Change |
| GSK1070806 Dose Level 3 | -41.49 ± 43.341 Percent Change |
| GSK1070806 Dose Level 4 | -58.08 ± 33.129 Percent Change |
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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