BENITIONSClinical Trial Intelligence

A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)

Фаза 3 Завершено NCT05899816

ЗаболеваниеAtopic Dermatitis, Moderate-to-severe Atopic Dermatitis
ФазаФаза 3
СпонсорAmgen
СтатусЗавершено
Участники221 участн.
ВмешательствоRocatinlimab
Дата начала7.06.2023
Дата завершения26.08.2024
Публикация результатов23.07.2026

Кратко

The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 24

Percentage of Participants With a Positive Anti-tetanus Response at Week 24

Week 20 to Week 24 · percentage of participants

Placebo92.3 percentage of participants
Rocatinlimab87.6 percentage of participants
Risk Difference (RD)-4.7 (95% CI -13.5–5.9)

Percentage of Participants With a Positive Anti-meningococcal Response at Week 24

Week 20 to Week 24 · percentage of participants

Placebo53.2 percentage of participants
Rocatinlimab52.5 percentage of participants
Risk Difference (RD)-0.7 (95% CI -18.3–17.1)

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