A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)
Фаза 3
Завершено
NCT05899816
| Заболевание | Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis |
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| Фаза | Фаза 3 |
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| Спонсор | Amgen |
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| Статус | Завершено |
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| Участники | 221 участн. |
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| Вмешательство | Rocatinlimab |
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| Дата начала | 7.06.2023 |
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| Дата завершения | 26.08.2024 |
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| Публикация результатов | 23.07.2026 |
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Кратко
The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 24
Percentage of Participants With a Positive Anti-tetanus Response at Week 24
Week 20 to Week 24 · percentage of participants
| Placebo | 92.3 percentage of participants |
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| Rocatinlimab | 87.6 percentage of participants |
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| Risk Difference (RD) | -4.7 (95% CI -13.5–5.9) |
Percentage of Participants With a Positive Anti-meningococcal Response at Week 24
Week 20 to Week 24 · percentage of participants
| Placebo | 53.2 percentage of participants |
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| Rocatinlimab | 52.5 percentage of participants |
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| Risk Difference (RD) | -0.7 (95% CI -18.3–17.1) |
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