PDA001 for the Treatment of Adults With Moderate-to-Severe Crohn's Disease
| Заболевание | Crohn's Disease |
|---|---|
| Фаза | Фаза 2 |
| Спонсор | Celularity Incorporated |
| Статус | Завершено |
| Участники | 50 участн. |
| Вмешательство | Human Placenta-Derived Cells PDA001 Intravenous Infusion, Vehicle Control |
| Дата начала | 08.2010 |
| Дата завершения | 02.2012 |
| Публикация результатов | 7.07.2026 |
Кратко
This Phase 2a study evaluated the efficacy, safety, and tolerability of intravenous human placenta-derived cells (PDA001) compared with placebo in adults with moderate-to-severe Crohn's disease. Three PDA001 dose levels were evaluated.
Percentage of Subjects With Clinical Response Based on Crohn's Disease Activity Index (CDAI) at Both Week 4 and Week 6
| 200 × 10^6 Cells of Human Placenta-Derived Cells PDA001 | 5 Participants |
|---|---|
| 800 × 10^6 Cells of Human Placenta-Derived Cells PDA001 | 5 Participants |
| Vehicle Control | 0 Participants |
| 1.6 × 10^9 Cells of Human Placenta-Derived Cells PDA001 | 2 Participants |
Открыть в BENITIONS Открыть на ClinicalTrials.gov
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