BENITIONSClinical Trial Intelligence

A Study of LY3885125 in Participants With Dyslipidemia or Non-Alcoholic Fatty Liver Disease (NAFLD)

1상 조기 종료 NCT06007651

대상 질환Dyslipidemias, Non-Alcoholic Fatty Liver Disease
임상 단계1상
스폰서Eli Lilly and Company
상태조기 종료
참여자 수49 명
중재(약물)LY3885125
시작일2023년 8월 10일
완료일2025년 2월 12일
결과 공개일2026년 4월 13일

요약

The main purpose of this study is to evaluate the safety and tolerability of LY3885125 after administration of single ascending doses in participants with dyslipidemia (part A) and multiple doses in participants with non-alcoholic fatty liver disease (part B). Blood tests will be performed to check how much LY3885125 gets into the bloodstream and how long it takes the body to eliminate it. The study will last up to approximately 49 weeks for part A and 62 weeks for part B, for a total of approximately 111 weeks.

Part A: Number of Participants With One or More Serious Adverse Event(s) Considered by the Investigator to be Related to Study Drug Administration

Baseline up to 36 weeks (Part A) · Participants

Part A: SAD Cohort 10 Participants
Part A: SAD Cohort 20 Participants
Part A: SAD Cohort 30 Participants
Part A: SAD Cohort 40 Participants
Part A: SAD Cohort 50 Participants
Part A: Placebo0 Participants

Part B: Number of Participants With One or More SAEs Considered by the Investigator to be Related to Study Drug Administration

Baseline up to 36 weeks (Part B)

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