Specific Electrophenotypes in Atrial Fibrillation
| 대상 질환 | Atrial Fibrillation |
|---|---|
| 임상 단계 | 단계 해당 없음 |
| 스폰서 | Imperial College London |
| 상태 | 조기 종료 |
| 참여자 수 | 1 명 |
| 중재(약물) | Biomarkers, electrocardiographic imaging, intracardiac electrograms, cardiac magnetic resonance imaging |
| 시작일 | 2022년 5월 19일 |
| 완료일 | 2024년 8월 27일 |
| 결과 공개일 | 2026년 3월 12일 |
요약
This study will investigate a common heart rhythm disturbance (arrhythmia), atrial fibrillation (AF), to improve understanding of how best to treat it in different patients. Direct current cardioversion (DCCV) is a procedure that can revert the heart to a normal rhythm, however almost all patients will only have a transient benefit, and their heart will return to the abnormal rhythm, AF. Ablation is an invasive procedure that creates scar tissue within the heart to reduce the arrhythmias, with a longer lasting effect than DCCV. It has been used with success in AF that occurs occasionally (paroxysmal) but is not as effective in AF that is more long-lasting, also known as persistent AF. Persistent AF is major cause of symptoms of breathlessness and palpitations and significantly increases the risk of stroke. Doctors are unable to accurately predict which patients will benefit most from an ablation, this can lead to as many as 50% of patients not benefitting from the procedure. The aim is to better predict which patients will benefit from an ablation. The study will include patients undergoing AF ablation or DCCV and perform additional tests including blood tests a heart MRI scan, a s
Freedom From Atrial Fibrillation
BENITIONS에서 보기 ClinicalTrials.gov 원문 보기
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