BENITIONSClinical Trial Intelligence

Specific Electrophenotypes in Atrial Fibrillation

該当なし 早期終了 NCT05366530

対象疾患Atrial Fibrillation
該当なし
スポンサーImperial College London
ステータス早期終了
参加者数1 名
介入(薬剤)Biomarkers, electrocardiographic imaging, intracardiac electrograms, cardiac magnetic resonance imaging
開始日2022年5月19日
完了日2024年8月27日
結果公開日2026年3月12日

概要

This study will investigate a common heart rhythm disturbance (arrhythmia), atrial fibrillation (AF), to improve understanding of how best to treat it in different patients. Direct current cardioversion (DCCV) is a procedure that can revert the heart to a normal rhythm, however almost all patients will only have a transient benefit, and their heart will return to the abnormal rhythm, AF. Ablation is an invasive procedure that creates scar tissue within the heart to reduce the arrhythmias, with a longer lasting effect than DCCV. It has been used with success in AF that occurs occasionally (paroxysmal) but is not as effective in AF that is more long-lasting, also known as persistent AF. Persistent AF is major cause of symptoms of breathlessness and palpitations and significantly increases the risk of stroke. Doctors are unable to accurately predict which patients will benefit most from an ablation, this can lead to as many as 50% of patients not benefitting from the procedure. The aim is to better predict which patients will benefit from an ablation. The study will include patients undergoing AF ablation or DCCV and perform additional tests including blood tests a heart MRI scan, a s

Freedom From Atrial Fibrillation

1 year

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